Acetonitrile for chromatogra 2,5 L

Understanding the chemical structure of acetonitrile clarifies its exceptional behaviour in chromatography: 

• Chemical Formula: C₂H₃N 

• Molecular Structure: Comprises a methyl group (–CH₃) connected to a nitrile group (–C≡N). 

• Molar Mass: 41.05 g/mol 

The linear configuration of the molecule facilitates efficient penetration into stationary phases, improving resolution in high-pressure chromatographic setups. Its minimal interaction with UV detectors enhances signal clarity in trace detection. 

This acetonitrile HPLC grade product is packaged and delivered with a focus on safety and analytical consistency: 

High-purity acetonitrile is produced through a tightly controlled process: 

• Raw Material Sourcing: Obtained from acrylonitrile byproducts or synthesized from ethylene and ammonia. 

• Initial Purification: Distilled under reduced pressure to eliminate water and volatiles. 

• Fine Filtration: Removes particles that may affect chromatography. 

• Polishing: Advanced adsorption removes UV-active impurities and trace metals. 

• Quality Testing: Each batch undergoes Karl Fischer, UV absorbance (210–280 nm), and acidity tests. 

• Inert Packaging: Bottled under nitrogen/argon to prevent degradation. 

Lab Chemicals ensures ISO-certified production for globally compliant HPLC-grade acetonitrile. 

Thanks to its high solvency and low interference characteristics, C₂H₃N finds diverse applications across industries: 

1. High-Performance Liquid Chromatography (HPLC) 

• Primary eluent in reversed-phase HPLC due to low viscosity and strong elution power. 

• Enables trace-level detection of pharmaceuticals, pesticides, and biomolecules. 

• Enhances resolution and peak sharpness in gradient and isocratic runs. 

• Often combined with 2-Propanol For HPLC to adjust polarity and enhance peak sharpness. 

2. Liquid Chromatography–Mass Spectrometry (LC-MS) 

• Compatible with electrospray ionization (ESI) interfaces 

• Provides a clean matrix with low background noise 

• Used in metabolomics, proteomics, and forensic toxicology 

3. Pharmaceutical Quality Control 

• Solvent in impurity profiling, assay development, and stability studies 

• Used in bioequivalence and pharmacokinetic testing 

4. Environmental & Food Testing 

• Extractant for pesticide and contaminant analysis in soil, water, and food matrices 

• Enables monitoring of endocrine-disrupting compounds, nitrates, and nitrites 

5. Industrial Processing 

• Applied in the manufacturing of synthetic fibres, batteries, and photochemical products in non-HPLC grade forms. 
• Employed in the fabrication of microelectronics and medical devices 

Acetonitrile chemical (C₂H₃N) is a highly versatile solvent prized for its polarity, low viscosity, and UV transparency—making it indispensable in HPLC and advanced chromatography. From pharmaceutical testing to environmental analysis, its reliability spans diverse applications. Lab Chemicals provides HPLC-grade acetonitrile in a 2.5 L variant, ensuring consistent quality and compliance with strict analytical standards. Backed by expert manufacturing and documentation, it's the trusted choice for precision-driven labs. 

Choose Lab Chemicals—where chromatography begins with confidence. 

What is Acetonitrile used for in HPLC? 

Acetonitrile HPLC is used as a high-purity mobile phase solvent due to its low UV absorbance, excellent miscibility with water, and ability to deliver sharp chromatographic peaks. 

What is the chemical formula of Acetonitrile? 

The molecular formula of acetonitrile is C2H3N, which represents its simple nitrile structure commonly used in analytical chemistry. 

Why is Acetonitrile preferred over other solvents in chromatography? 

Acetonitrile chemical offers low viscosity, strong elution strength, and fast column equilibration, making it a preferred solvent for separating complex organic compounds. 

Does Acetonitrile leave residue after evaporation? 

No. Acetonitrile chemical evaporates cleanly with negligible residue, making it ideal for sample preparation and solvent exchange. 

Is HPLC-grade Acetonitrile different from regular laboratory-grade acetonitrile? 

Yes. Acetonitrile HPLC undergoes advanced purification to remove UV-active impurities and moisture, ensuring stable baselines and reproducible results.