N,N-Dimethylformamide (DMF, CAS No. 68-12-2), also known as nn dimethyl formamide, is a polar, hygroscopic solvent widely used in analytical, industrial, and pharmaceutical applications. This colorless liquid offers excellent solvency, thermal stability, and low residue. In GC-grade form, it’s ideal for residual solvent analysis and headspace GC, ensuring high purity and precision. DMF’s broad compatibility with organic and inorganic compounds makes it essential for quality control and pharmaceutical compliance workflows.
The value of N,N-Dimethylformamide in analytical chemistry stems from a unique combination of chemical properties:
These properties make nn dimethyl formamide ideal for accurate, reliable performance in headspace GC and residual solvent analysis across diverse chromatographic techniques.
Similar properties are found in high-purity solvents like Acetonitrile – 2.5L, commonly used in GC and HPLC for low UV absorbance and volatility.
Understanding the structure of N,N-Dimethylformamide explains its superior solvency and wide compatibility:
As a tertiary amide, DMF exhibits a polar aprotic nature, enabling it to dissolve both polar and non-polar compounds—crucial for efficient sample extraction and preparation in trace-level analysis.
Dimethylformamide stands out in analytical labs due to its manageable and efficient physical profile:
| Attribute | Specification |
| Appearance | Clear, colourless, and hygroscopic liquid |
| Odor | Slight fish-like smell (common with amides) |
| Evaporation Rate | Moderate; facilitates easy solvent recovery and drying |
| Flash Point | 58°C (closed cup) – caution required during storage and handling |
| Packaging Options | Amber glass bottles, aluminium cans, HDPE drums, and stainless-steel IBCs |
| Handling Advice | Use in well-ventilated areas with PPE (gloves, goggles, lab coat); store away from open flames and oxidizers |
GC-grade DMF is produced through a precise multi-step process to ensure ultra-high purity:
At Lab Chemicals, each batch of N,N-Dimethylformamide meets strict GC-grade standards for dependable analytical performance.
Owing to its purity, polarity, and solubility, DMF finds application across several industries, particularly in analytical and quality control environments:
Residual Solvent Analysis:
Headspace Gas Chromatography:
Pharmaceutical & Chemical Synthesis:
Electronics & Polymer Industry:
Research & Academia:
N,N-Dimethylformamide (C₃H₇NO, CAS No. 68-12-2) is a highly polar solvent ideal for residual analysis and headspace GC, offering clean baselines and reliable reproducibility. Lab Chemicals provides GC-grade nn dimethyl formamide crafted under strict quality control to meet top analytical and regulatory standards. Trusted in pharma, environmental testing, and R&D, our DMF ensures precise, compliant workflows. Choose Lab Chemicals—where analytical accuracy starts with high-purity solvents.
Understanding the structure of N,N-Dimethylformamide explains its superior solvency and wide compatibility:
As a tertiary amide, DMF exhibits a polar aprotic nature, enabling it to dissolve both polar and non-polar compounds—crucial for efficient sample extraction and preparation in trace-level analysis.
Dimethylformamide stands out in analytical labs due to its manageable and efficient physical profile:
| Attribute | Specification |
| Appearance | Clear, colourless, and hygroscopic liquid |
| Odor | Slight fish-like smell (common with amides) |
| Evaporation Rate | Moderate; facilitates easy solvent recovery and drying |
| Flash Point | 58°C (closed cup) – caution required during storage and handling |
| Packaging Options | Amber glass bottles, aluminium cans, HDPE drums, and stainless-steel IBCs |
| Handling Advice | Use in well-ventilated areas with PPE (gloves, goggles, lab coat); store away from open flames and oxidizers |
GC-grade DMF is produced through a precise multi-step process to ensure ultra-high purity:
At Lab Chemicals, each batch of N,N-Dimethylformamide meets strict GC-grade standards for dependable analytical performance.
Owing to its purity, polarity, and solubility, DMF finds application across several industries, particularly in analytical and quality control environments:
Residual Solvent Analysis:
Headspace Gas Chromatography:
Pharmaceutical & Chemical Synthesis:
Electronics & Polymer Industry:
Research & Academia:
N,N-Dimethylformamide (C₃H₇NO, CAS No. 68-12-2) is a highly polar solvent ideal for residual analysis and headspace GC, offering clean baselines and reliable reproducibility. Lab Chemicals provides GC-grade nn dimethyl formamide crafted under strict quality control to meet top analytical and regulatory standards. Trusted in pharma, environmental testing, and R&D, our DMF ensures precise, compliant workflows. Choose Lab Chemicals—where analytical accuracy starts with high-purity solvents.
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